Vitamin E Acetate: Looking Behind the Label
Historical Development
The story of Vitamin E Acetate gets pretty interesting right out of the gate. It’s not as old as Aspirin or as mysterious as penicillin mold, but its roots go back almost a century. Chemists identified Vitamin E in the 1920s, and before long, they started tinkering with it, aiming to protect this finicky compound from oxidation. Out of that effort grew the idea to modify it, attaching an acetate group and creating a much more stable form. This tweak paid off. By the 1940s and 1950s, Vitamin E Acetate showed up in supplements, skin creams, and feedstock. The public didn’t notice when labs swapped in the acetate version, but industry sure did—this allowed shipping and storing without the threat of it going rancid or losing potency. As demand grew for shelf-stable vitamin blends and affordable skincare, factories churned out barrels of oily, nearly odorless Vitamin E Acetate. Its place in dozens of industries today can be traced to those early years when stability drove innovation.
Product Overview
Vitamin E Acetate, or tocopheryl acetate, stands out from other vitamin compounds because of this chemical stability. Most consumers run into it through capsules at the pharmacy, blended into lotions, or mixed in multivitamin gummies. It brings the benefits of Vitamin E—support for cell membranes and help warding off oxidative stress—yet it doesn’t spoil as quickly in the bottle or jar. Companies in the food, cosmetic, and pharmaceutical fields praise this stuff because it handles shipment, storage, and processing better than the natural tocopherol form. In my experience, anyone reading a label for a skin cream, shampoo, or wellness product likely spots “tocopheryl acetate” midway down the list. This ingredient, usually derived from vegetable oils, is a mainstay across dozens of product lines, from drugstore deals to premium skincare imports.
Physical & Chemical Properties
Vitamin E Acetate usually shows up as a viscous, clear yellow oil. Unlike raw tocopherol, which reacts to air and light, this version keeps its color and thick texture even after months on a shelf. Its melting point hovers between 28 and 31°C, which means it stays liquid in most home and factory settings. This makes dosing simple, whether pouring it into nutrition capsules or blending into a vat of moisturizer. Water won’t dissolve it, but it mixes well with most common cosmetic or food-grade oils. Its stability under normal conditions keeps both manufacturers and end users happy, reducing the risk of product spoilage or loss of potency. I’ve seen small makers store big drums with minimal precautions—just keep it away from strong acids or prolonged sunlight, and shelf life stretches years without drama.
Technical Specifications & Labeling
Most labels and technical sheets for Vitamin E Acetate look for a purity north of 98%, with tocopheryl acetate listed as the principal active. Regulatory agencies watch for contaminant levels, especially as compounds like dioxins or heavy metals can sneak in during large-scale synthesis. FDA and EU rules demand clear labeling for both finished blends and bulk shipments, using official ingredient names and listing standard units (usually IU or mg for supplements). For creams and lotions, it often appears below trade names or in the INCI (International Nomenclature Cosmetic Ingredient) form, “tocopheryl acetate.” Label-wise, consumers get a relatively straightforward message, but behind the scenes, manufacturers send out certificates of analysis, detailing not just Vitamin E content but also heavy metal screenings, microbiological checks, and batch traceability. These technical specs help maintain trust from both regulators and customers.
Preparation Method
Building Vitamin E Acetate in the lab is not something you’d try at home. Chemists start with the vitamin’s active alcohol form, usually dl-alpha-tocopherol, freshly distilled from natural vegetable oils or made via total synthesis. This raw tocopherol can go bad quickly, so manufacturers react it with acetic anhydride, a common acetylating agent. This simple reaction, catalyzed by a mild acid, swaps a hydrogen group on the tocopherol for an acetate group. The end result is a far less reactive compound whose antioxidant properties only spring into full effect once metabolized inside the body. The effluent and spent solvents from this process demand careful disposal, which means factories build in reclamation or scrubbing phases before sending anything for recycling or incineration. This step ensures the product shipped on pallets or tanker trucks meets tight safety and purity standards, ready for blending into hundreds of commercial uses.
Chemical Reactions & Modifications
Tocopheryl acetate stands out mostly for what it doesn’t do. It doesn’t react with air or light easily and lives through normal heating that would destroy raw tocopherol. That said, it’s not inert across the board. In the body, enzymes in the gut and liver snip off the acetate, releasing active Vitamin E. In a chemistry lab, strong reduction or hydrolysis can return it to tocopherol, allowing for further modification. Chemists have played with this backbone, adding or swapping other groups to tailor properties for research or for specialized applications like slow-release formulas or targeted delivery carriers. In my time testing lotion prototypes, we found it stubbornly resisted breaking down unless we brought out tougher reagents—useful for product stability, but requiring careful design for any intended bioactivity. Research into further tweaking Vitamin E Acetate’s core keeps pushing both formulation science and delivery strategies forward.
Synonyms & Product Names
People know this compound under an army of names, thanks to global branding, regulatory codes, and marketing choices. On ingredient labels, look for “dl-alpha-tocopheryl acetate,” “Vitamin E Acetate,” or “all-rac-alpha-tocopheryl acetate.” In scientific circles, CAS Number 7695-91-2 pins it down unambiguously. Cosmetic packaging leans on “tocopheryl acetate,” which fits with international labeling codes. Major chemical suppliers brand it with catalog numbers or trade names—nothing exotic, but enough to keep procurement departments busy matching specs. Over the years, some producers have offered “mixed tocopheryl acetates” from blended natural sources, but the bioactivity and chemical skeleton don’t really change.
Safety & Operational Standards
Operators handling Vitamin E Acetate rely on standard precautions for viscous food-grade or cosmetic oils. This material presents low acute toxicity, so the bigger risks tend to center on the solvents or residues from upstream production. FDA, EMA, and similar bodies set daily intake limits to guard against chronic over-consumption, and these limits drive formulation choices in supplements and functional foods. Factory workers get fitted with basic gloves and splash goggles, as the compound can irritate eyes or skin in high concentrations or after repeated contact. GMP (Good Manufacturing Practice) audits focus on process hygiene, record-keeping, and traceability, with routine checks for cross-contamination, degradation, and foreign matter. Distribution always tracks temperature and exposure history—warm and dark works best, with constant monitoring for any breakdown products. Mixing this compound into finished products remains straightforward, but it never pays to ignore the rules or paperwork, especially for exports or pharmaceutical-grade production.
Application Area
Vitamin E Acetate spans a wide territory. Skincare companies rely on it for sunburn creams, anti-aging serums, and simple body lotions because it holds up to harsh manufacturing processes and extends shelf life—even if only a fraction ever gets converted to active Vitamin E by the skin. Multivitamin makers use it for chewable tabs and tablets, counting on its stability and measured potency. Food producers sometimes add it as an antioxidant preservative in processed foods or edible oils, though this isn’t nearly as common as in the supplement aisle. In animal feed, it supports livestock health and cuts spoilage rates. A few years ago, new uses appeared in the vaping industry, but cases of severe lung illness pushed health agencies into action, restricting such applications due to real safety questions. For practical daily use, most people experience Vitamin E Acetate through over-the-counter pills, creams, and fortified foods.
Research & Development
Researchers still look for new angles on Vitamin E Acetate—whether tweaking the core to boost absorption, engineering slow-release forms, or developing new analytical testing routes for product verification. Teams across the globe run trials on topical delivery, wound healing, and improved oral formulations that reach tissues more efficiently. Analytical chemists chase more sensitive and accurate tests for trace contaminants, as consumer watchdog groups keep companies on their toes. Tech transfer groups look for ways to “green” manufacturing and lower both solvent and energy footprints. Basic research continues to refine our understanding of how Vitamin E Acetate moves through the human body, especially how quickly it converts to active forms in different tissues. Some teams are even using its backbone for specialty drug delivery or nanocarriers targeting stubborn medical conditions, though that’s still mostly in the animal-testing stage.
Toxicity Research
Toxicity studies tell a nuanced story. In standard dosages, dietary supplements and skin applications rarely cause trouble. Chronic overuse—especially via injection or inhalation—can cross into dangerous zones. That vaping crisis from 2019 put Vitamin E Acetate into the headlines, with evidence showing its link to severe vaping-related lung injuries. It turns out, the acetate form, inhaled as oil droplets, mucked up the lungs in ways no oral supplement would. Regulators responded quickly, slapping new warnings on high-purity product shipments and restricting certain uses in inhaled products. On the digestive side, studies suggest the body efficiently cleaves the acetate group, with excretion of surplus via urine and bile. Still, people with certain fat-absorption disorders or rare genetic issues could face trouble assimilating even modest doses. Companies track new research closely, as unexpected findings can change labeling, dosing, or even market status overnight.
Future Prospects
Looking ahead, Vitamin E Acetate faces both new challenges and opportunities. The supplement industry shows steady demand for shelf-stable antioxidants, and skin-care brands show no sign of scrapping it as a formulation mainstay. Green chemistry—lowering environmental impact of large-scale production and purification—offers an active area for process innovation. Regulations now respond faster to risk signals, especially for non-oral applications and new delivery systems. Drug researchers are testing slightly modified versions for medical delivery, aiming for treatments that tap Vitamin E’s antioxidant profile but deliver it more precisely. Consumer demand for “clean labels” and natural sourcing pushes companies to refine extraction and purification, minimizing contaminants and tracking full ingredient chains. Future breakthroughs could involve hybrid molecules, smarter dosing, and applications outside the current supplement and cosmetic aisles. Still, safety, label transparency, and ongoing bioactivity research remain top priorities for anyone in the field—whether in the lab or on the factory floor.
The Familiar Side: Skin, Food, and Supplements
Most people recognize Vitamin E from shopping trips to the pharmacy or the beauty aisle. Products boasting antioxidant claims can fill up a whole shelf. Vitamin E acetate, a synthetic form of Vitamin E, shows up in many of these products for good reason. It protects against the kind of cell damage that can dry out skin, fade hair color, or wreck what dermatologists call the "skin barrier."
Think about dry elbows in the winter. A cream with Vitamin E acetate often does the trick. This ingredient steps up in lotions, face serums, and sunscreen, shielding your skin from the free radicals produced by sun and pollution. Brands use Vitamin E acetate because natural Vitamin E loses potency fast when exposed to air and light. That extra “acetate” tail sticks to the molecule and helps it last through storage and usage.
Beyond skincare, Vitamin E acetate finds a place in the nutrition aisle. Vitamin companies mix it into their tablets and capsules because it holds up better than natural Vitamin E. It survives warehouse storage, resists breakdown, and arrives in your home with more power leftover.
Unexpected Corners: Industry and Controversy
It surprises some people to learn that Vitamin E acetate plays a role outside of personal care and supplements. Food manufacturers often include it as an additive to protect oils and processed snacks from going rancid. Fats spoil faster without antioxidants, and Vitamin E acetate slows that process, making potato chips and salad dressings last longer.
Things got complicated in recent years when Vitamin E acetate entered the spotlight for all the wrong reasons. Some producers put it into illicit vaping cartridges to dilute THC oil, mainly because it's cheap and looks like pure cannabis extract. This shortcut turned risky. In 2019, the Centers for Disease Control and Prevention (CDC) found Vitamin E acetate at the heart of thousands of lung injuries among vape users. Under normal conditions—applied on the skin or swallowed by mouth—Vitamin E acetate remains safe. It does not belong in the lungs. Heating and inhaling this oil damages fragile lung tissue, causing a cluster of illnesses that doctors hadn’t seen before.
Lessons Learned and Paths Forward
The story of Vitamin E acetate says a lot about how context changes the safety of familiar ingredients. On my own kitchen shelf, I keep a moisturizer with Vitamin E acetate for my hands. I think about every passing year, seeing more research calling out the nuance around “safe” and “unsafe” uses. Studies cited by organizations like the Food and Drug Administration (FDA) and CDC make clear distinctions between ingesting this ingredient and inhaling it as an aerosol.
It helps to push for stronger oversight and clearer labeling. No one expects a vitamin used in skincare products to cause lung injuries when misused. Regulators can keep up by tracking the shifting markets and making it tougher for unsafe uses to sneak into unregulated products. On an individual level, everyone can read labels closely—watch what goes on the skin and stays out of the lungs.
Vitamin E acetate shows up all around us, from tubs of face cream to the ingredient list on cereal boxes. The big takeaway: an ingredient’s role can flip with a change in use. Paying attention to those details could save a lot of trouble down the road.
Everyday Experience with Vitamin E in Skincare
People reach for creams and serums with Vitamin E whenever dryness or flakiness hits. Many dermatologists recommend Vitamin E, particularly its acetate form, because it keeps the formula stable longer on the store shelf. The molecule resists oxidation, so your lotion won’t lose its punch before you even open it. For most folks, using Vitamin E acetate in a skin product feels comforting and seems safe. Even my own skin, which breaks out at the mere hint of fragrance, usually acts calm with Vitamin E blends.
What the Research Says
Scientific reviews and clinical studies give Vitamin E a solid track record for moisturizing benefits. Vitamin E acetate works by converting to free Vitamin E (tocopherol) on the skin, which can help reinforce the skin barrier. One peer-reviewed study in the British Journal of Dermatology found topical Vitamin E reduced redness after sunburn. Other research links antioxidant effects with a visible reduction in fine lines, which draws a lot of people chasing “glow” into the Vitamin E aisle.
Despite the positives, it’s not 100% trouble-free. Cases of allergic reactions have cropped up, especially in people who already deal with skin sensitivities. These incidents remain rare compared to the millions of people who use Vitamin E daily. Experts emphasize patch tests for new products, especially for those who struggle with eczema or frequent rashes.
Sticking Point: The Vaping Controversy
A few years ago, some panic swept through the news after Vitamin E acetate showed up in vaping liquid linked to lung injuries. That situation lit up health forums and forced a closer look at Vitamin E’s safety in every context. It helped clarify something crucial: what’s dangerous in your lungs isn’t automatically bad on your skin. Studies confirm that Vitamin E acetate doesn’t get into the bloodstream in significant amounts through healthy skin. The skin acts like a shield, making topical use very different from inhaling something deeply into the lungs. Both the American Academy of Dermatology and Mayo Clinic find Vitamin E acetate safe in skin care, as long as no one swallows or inhales it.
Who Should Be Careful
People with nut allergies sometimes worry about Vitamin E, since most natural Vitamin E gets extracted from soybeans or sunflower seeds. Highly refined forms rarely cause allergic reactions, but people with severe food allergies might still want to check labels and consult with a dermatologist. Patch testing at home offers a simple way to play it safe: dab a bit on the inner elbow and check for itching or redness the next day.
Making Better Choices with Skincare
Looking for a solid moisturizer, skip the hyped-up promises and pay attention to ingredient lists. More is not always better, especially if your skin reacts easily. Doctors often suggest starting with lower concentrations of Vitamin E acetate and using it every other day before ramping up. If skin tingles, blisters, or stays itchy, swap it out. Keep your skincare simple, pick fragrance-free products, and ask for professional advice if you feel unsure.
Everyone’s skin tells a different story, so one skincare winner for you might not suit someone else. Vitamin E acetate works for the vast majority, but listening to your own skin should steer your decisions—and new science always deserves a spot in that conversation.
Vitamin E Acetate: What It Is
Vitamin E acetate, also called tocopheryl acetate, is a form of vitamin E found in many supplements and skincare products. It acts as an antioxidant, helping the body defend itself against free radicals and cell damage. Vitamin E comes in several forms, and acetate is one of the most stable types, with a longer shelf life than the pure vitamin E alcohol form.
Supplements and Safety: Digging into the Facts
Some vitamin E supplements on the shelf use the acetate version. This form travels through your digestive system, gets converted in the body to active vitamin E, and provides similar benefits. The U.S. National Institutes of Health states that both natural and synthetic forms of vitamin E—including acetates—are legal to use as supplements and have a history of safe use when taken by mouth at recommended doses. High doses, though, can increase the risk of bleeding, especially for people on blood-thinning medicine. Too much has even shown potential to cause other issues such as nausea or headaches.
If you flip the bottle and see “dl-alpha-tocopheryl acetate,” you’re looking at the synthetic form. It costs less but is a bit weaker than the “d-alpha-tocopherol” natural type. Your bloodstream absorbs both, and they both act as antioxidants in the body. The synthetic form provides about half as much biologically active vitamin E by weight as the natural type. Most healthy adults actually get enough vitamin E from diet—nuts, seeds, green leafy vegetables, and plant oils pack plenty of it.
Why Vitamin E Acetate Got a Bad Rap
The mention of vitamin E acetate sometimes raises concerns because of reports linking it to severe lung injury. Those cases were tied to vaping, not to swallowing capsules. Vitamin E oil, when heated and inhaled, can seriously damage the lungs, but there’s no evidence that swallowing it in supplement form causes the same harm. The U.S. Centers for Disease Control and Prevention traced most of the lung cases to inhaled vitamin E acetate rather than ingestion.
Practical Advice before Adding Supplements
Before popping any new vitamin for health, consider a few real-world points. As someone who likes real food, I look for most nutrients at the grocery store. For most people eating a balanced diet, extra vitamin E makes little difference, and almost all of us can cover the recommended daily intake through food. Older adults, people with fat malabsorption issues, or those with very restricted diets sometimes come up short and may benefit from an extra boost. Still, a doctor’s advice helps more than random internet tips or slick marketing from supplement companies.
Some everyday folks have told me they saw claims that vitamin E does wonders for the skin, hair, and immune system. Those benefits mostly come from getting enough, and current studies do not support megadoses. Some years ago, I tried a high-dose supplement hoping for more youthful skin and zero colds. What happened? No noticeable changes except a lighter wallet and occasional stomach upset from too many pills.
Better Choices and Moving Forward
The supplement world thrives on trends, but evidence shows that more isn't always better—especially with fat-soluble vitamins like this one. Talking with a doctor matters if you're considering big doses or have health concerns. For almost everyone else, real food gets the job done. Skipping the hype and sticking to science protects your mind, wallet, and long-term health.
Not All Vitamins Are Created Equal
People hear “vitamin E,” and most picture tiny golden capsules in a bottle marked as good for your skin and immune system. In its natural form, vitamin E grabs lots of attention for possible heart and skin benefits. There’s a synthetic version many may never think twice about—vitamin E acetate. You’ll see it on ingredients lists, especially in beauty products and some dietary supplements. The trouble started when researchers linked vitamin E acetate to serious lung injury, raising questions that never existed for traditional vitamin E.
What Happens When Vitamin E Acetate Ends Up in Your Lungs?
Nothing brought this synthetic version into public debate quite like the 2019 outbreak of vaping-related lung injuries known as EVALI. Hundreds landed in hospitals, many struggling to breathe, and several lost their lives. The CDC singled out vitamin E acetate as a thickener in some vaping liquids. There’s no proof it causes trouble when you eat or use it on your skin, but inhaling it into your lungs is a different story. The chemical doesn’t belong there, and it appears to turn into something sticky and hard to clear out. The lungs aren’t built to break down these oily substances, so they get overwhelmed. I’ve talked with doctors who saw healthy young people gasping for air, and that impact stays with you.
What About Putting It on Your Skin?
Many use creams containing vitamin E acetate hoping for softer, smoother skin. For most, these lotions cause few problems. Sometimes people with sensitive skin may notice itching, redness, or a rash. These reactions pop up more often if you have eczema or allergies. I know folks who swear vitamin E makes their scars lighter; others break out after just one use. Patch testing before spreading something new across your face helps avoid a nasty surprise if you’re prone to irritation. Thankfully, reports of serious effects in topical use remain rare.
Swallowing Vitamin E Acetate—Safe or Not?
Swallowing supplements with vitamin E acetate at normal doses looks safe for most. High doses can thin the blood, and long-term, there’s some concern over increased bleeding risk, especially for those on certain medicines like warfarin. Too much can trigger headaches or stomach troubles. The FDA suggests daily vitamin E from all sources, natural or synthetic, should stay below 1,000 mg. Most people never come close to that level from food and vitamins combined. If you already take multiple supplements, double-check the labels, and talk with your health provider about doses.
What Do Experts Recommend?
Experts I’ve spoken to always highlight common sense—avoid inhaling ingredients never made for your lungs. The CDC, FDA, and several state health agencies now warn against vaping anything with vitamin E acetate. For topical use, safer bets include spot tests for anyone with sensitive or allergy-prone skin. With supplements, more is not always better. Review ingredient lists, stick to recommended doses, and find quality products with third-party testing.
Smart Choices Moving Forward
The EVALI outbreak offered a hard lesson: not every form of a vitamin is harmless. Health-conscious people look for pure, tested products and steer clear of unwanted additives in vaping items. Honest labeling and clearer warnings would help. It makes sense to demand transparency about what goes into products touching your body or entering your lungs. Consumers, makers, and regulators all carry a piece of responsibility to keep vitamin E acetate use safe.
Protecting Potency with Simple Steps
Vitamin E Acetate has found its way into supplements, skin-care routines, and pharmaceutical prep rooms. Over-the-counter options and bulk containers both line drugstore shelves. What often gets missed is how important the right storage is to protect its quality and safety.
Many in the nutrition and wellness field share a common experience: you leave a bottle of vitamins on a sunny bathroom shelf, and after a few weeks, the capsules stick together or smell strange. That’s not by accident but by science. Vitamin E Acetate, like many oil-based vitamins, breaks down in heat, sunlight, and damp conditions. My work in clinical settings has shown that the potency of a vitamin drops fast when stored in hot or humid environments. The label might promise a certain dose, but reality tells a different story if the vitamin isn’t protected.
Temperature and Light Factor In
Sunlight turns pure Vitamin E Acetate cloudy. Heat can make the oil go rancid. These details matter, especially to families hoping to support health or companies producing supplements meant to last months on warehouse shelves. Keeping it cool and out of the light means storing it in a cabinet or drawer. Draw on your own kitchen habits: olive oil loses flavor left near the stove, and vitamins do much the same sitting on a windowsill. A room between 15 and 25°C avoids that sharp drop in shelf life. I’ve visited supplement packagers who use dark glass bottles for exactly this reason—the less light, the better.
Sealing Out Air and Water Improves Safety
Vitamin E Acetate can react with oxygen and moisture. A half-empty container left without a tight cap collects humidity, which triggers spoilage. Keeping lids tightly screwed on isn’t just good housekeeping; it keeps every dose closer to what the bottle claims. This lesson hit home early in my career when a patient’s supplements clumped together on a shelf near a steamy shower. After a quick audit, the solution looked simple: airtight containers, kept far from heat and steam. Good habits here help folks avoid costly waste and side effects from degraded vitamins.
The Importance of the Right Packaging
Packaging plays a bigger role than most realize. Dark amber bottles, or even opaque containers, protect against UV exposure. This isn’t marketing hype. Glass, rather than plastic, often stops chemical leaching and cross-reactions, especially important for folks with sensitivities. On a broader scale, manufacturers following good manufacturing practice (GMP) standards choose those materials based on long-term stability studies rather than cost alone.
Lessons from Mishandling
Some stories from the field aren’t pretty. In high school, the coach handed out vitamin capsules kept for months in a hot gym closet. Several students complained about odd tastes and stomach upset. Now, as a parent and nutrition advocate, that memory shapes my advice to others: store vitamins the way you keep good olive oil or medicine—cool, dark, and sealed.
Conclusion
Caring for Vitamin E Acetate isn’t complicated, but it calls for attention to details that busy people overlook. A little extra care on the shelf brings confidence in what we take and give to our families. Looking after it right means less waste, more value, and better results. Tucking a bottle inside a cool pantry or medicine cabinet and screwing the cap tight preserves strength and safety without extra effort.
| Names | |
| Preferred IUPAC name | (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl acetate |
| Other names |
dl-alpha-Tocopheryl acetate
all-rac-alpha-Tocopheryl acetate Vitamin E, acetate Tocopherol acetate α-Tocopheryl acetate Acetate of vitamin E |
| Pronunciation | /ˈvaɪtəmɪn iː ˈæsɪteɪt/ |
| Identifiers | |
| CAS Number | 58-95-7 |
| Beilstein Reference | 1711046 |
| ChEBI | CHEBI:31991 |
| ChEMBL | CHEMBL1207 |
| ChemSpider | 21172320 |
| DrugBank | DB11095 |
| ECHA InfoCard | 100.033.805 |
| EC Number | EC 2.3.1.135 |
| Gmelin Reference | 130831 |
| KEGG | C02477 |
| MeSH | D000701 |
| PubChem CID | 5280483 |
| RTECS number | KIY30000NQ |
| UNII | 3A7HDV5YKA |
| UN number | UN2810 |
| CompTox Dashboard (EPA) | DJ68D4A13S |
| Properties | |
| Chemical formula | C31H52O3 |
| Molar mass | 472.8 g/mol |
| Appearance | Clear, yellow, viscous oil |
| Odor | Odorless |
| Density | 0.950 g/mL |
| Solubility in water | Insoluble in water |
| log P | 6.1 |
| Vapor pressure | Negligible |
| Acidity (pKa) | 12.0 |
| Basicity (pKb) | 8.09 |
| Magnetic susceptibility (χ) | -9.29×10⁻⁶ cm³/mol |
| Refractive index (nD) | 1.494 |
| Viscosity | Viscous liquid |
| Dipole moment | 3.0227 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 1084.3 J·mol⁻¹·K⁻¹ |
| Std enthalpy of combustion (ΔcH⦵298) | -10116.8 kJ/mol |
| Pharmacology | |
| ATC code | A11HA03 |
| Hazards | |
| Main hazards | May cause respiratory irritation. May cause damage to organs through prolonged or repeated exposure. |
| GHS labelling | GHS07, GHS08 |
| Pictograms | GHS07,GHS08 |
| Signal word | Warning |
| Hazard statements | H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation. |
| Precautionary statements | Keep container tightly closed. Store in a cool, dry place. Avoid contact with eyes, skin, and clothing. Wash thoroughly after handling. |
| NFPA 704 (fire diamond) | 1-1-0 |
| Flash point | 254 °C |
| Autoignition temperature | 343 °C |
| Lethal dose or concentration | LD50 (Rat, oral): > 7000 mg/kg |
| LD50 (median dose) | LD50 (median dose) of Vitamin E Acetate: "4000 mg/kg (rat, oral) |
| NIOSH | HAZ70080 |
| PEL (Permissible) | 10 mg/m³ |
| REL (Recommended) | 15 mg |
| Related compounds | |
| Related compounds |
Vitamin E
Vitamin E succinate Vitamin E phosphate Vitamin E nicotinate |
