Diacetin: A Deep Dive Into Its Substance and Significance

Historical Development

Diacetin brings with it a century-long journey, winding through layers of chemical exploration, patent filings, and industrial scale-ups. Glycerol esters earned attention during the early days of organic chemistry, helping drive advancements in both technology and practical household products. Diacetin, also recognized as glycerol diacetate, surfaced as part of that broader research into versatile esters. Chemists in the twentieth century zeroed in on its value not only as a raw chemical but as a hardworking ingredient wherever a balance of solubility, plasticity, and mildness mattered. Commercial uses took off after the food sector, plastics fabrication, and cosmetic spheres discovered they could rely on this substance to fine-tune properties in everything from chewing gum to film manufacture. The knowledge base grew alongside improvements in distillation, esterification, and safety oversight, confirming that diacetin held a stable place among multi-purpose food additives and process auxiliaries.

Product Overview

Diacetin stands as a clear, colorless liquid with a light, pleasant odor. Its identity lies in being a diester formed from glycerol and acetic acid, creating a compound appreciated for both its purity and irritation-free nature in most applications. Producers gravitate toward diacetin in areas calling for solvency without hazards, mild plasticization effects, or embeddable flavor nuances. Many know it as E1517 on food ingredient labels; it thrives as both ingredient and process aid. In the consumer’s eye, diacetin shows up tucked into everything from low-fat spreads to pharmaceutical capsules, thanks to its proven track record in safety and formulation flexibility. Out on the market, it goes by several trade names, crossing boundaries between food-grade and industrial variants.

Physical & Chemical Properties

At room temperature, diacetin pours flowing and smooth, with a viscosity that lets it mix readily with most common solvents, including alcohol, ether, and water. Its molecular structure brings two acetate groups linked via ester bonds to a single glycerol backbone, lending it a reliable melting point near -30°C and a boiling point stretching over 284°C. This liquid doesn’t freeze on the shelf, doesn’t scorch in standard process conditions, and displays low volatility. Chemists appreciate its moderate polarity, which ensures active but not overly aggressive participation in mixtures. Colorless and low-odor by nature, it refuses to affect the appearance or scent of most final products—a trait valued by food scientists and manufacturers of delicate materials alike.

Technical Specifications & Labeling

Stringent oversight defines diacetin’s path from factory floor to finished product. Food-grade batches must showcase a purity of at least 98%, with minuscule traces of residual acetic acid and glycerol kept below allowed parts per million. Industry standards lay out limits for acidity, color (measured as APHA, or platinum-cobalt units), heavy metals, and moisture content. On a product label, diacetin appears as E1517 in the food world, while technical supply comes stamped with “glycerol diacetate” or “glyceryl diacetate.” Marked as not being allergenic and not genetically modified, it slips neatly into clean-label product strategies and passes scrutiny by both EFSA and FDA guidelines. Safety datasheets itemize hazard ratings as minimal under ordinary handling but emphasize care to avoid ingestion of undiluted product or excessive exposure to vapors in tight spaces during manufacturing.

Preparation Method

Manufacturers synthesize diacetin through a controlled esterification process, where glycerol and acetic acid meet under the influence of strong acid catalysts. The process unfolds in heated reactors, where care taken with ratios of glycerol to acetic acid determines formation of mono-, di-, or tri-acetins. Temperature and reaction timing play crucial roles: too short, and yields run low; too long, and unwanted byproducts intrude. Once the reaction reaches its endpoint, chemists use vacuum distillation to separate diacetin from both unreacted materials and higher esters. Filtration and final distillation steps polish the product, securing all key performance parameters. This hands-on refinement makes diacetin consistently reliable across large production batches.

Chemical Reactions & Modifications

Chemists know diacetin for its predictable response in further esterification or hydrolysis. Those acetate bonds can be broken down with acid or alkali, yielding back glycerol and acetic acid—a trait handy in both analytical testing and environmental breakdown. Diacetin may accept further modification to produce triacetin (glycerol triacetate), a closely related compound with even greater solvency or plasticizing punch. It holds up well under mild oxidizing or reducing conditions, bringing peace of mind for formulators who need stable ingredients across harsh production cycles. In specialized labs, diacetin serves as a platform for more exotic substituted esters, feeding curiosity in search of bio-based plasticizers and specialty solvents. Every adjustment along the chemical pathway creates a ripple in performance, allowing scientists in both industry and academic fields to home in on exactly what a new project requires.

Synonyms & Product Names

Diacetin pops up in supply catalogs under several monikers—glyceryl diacetate, diacetyl glycerol, E1517, and 1,2/1,3-glycerol diacetate all trace back to this same base structure. Tradenames shift, depending on end use and jurisdiction, but the chemistry beneath always echoes that hallmark blend of acetyl and glycerol. Food labels and cosmetic ingredient panels often opt for “glyceryl diacetate,” offering consumers a connection to familiar raw substances. Technical standards refer to either CAS 25395-31-7 for clarity or spell out the composition in full, especially when bulk buyers look for a trusted sourcing partner. Global databases, such as the European Inventory of Existing Commercial Chemical Substances (EINECS), confirm its accepted presence on world markets.

Safety & Operational Standards

Production plants handling diacetin operate by clear housekeeping: eye shields, glove protocols, strict ventilation, batch release testing, and full traceability run as daily norms. The mild nature of the liquid doesn’t excuse carelessness, especially in food and pharmaceutical environments where hygiene requirements hit the top of the scale. Safety benchmarks follow guidance set by the Food Chemicals Codex and REACH regulations. Hazard warnings list slight risk of mild eye and skin irritation and reinforce the importance of not ingesting the raw compound directly. During transfer, suppliers recommend sealed pumping systems and close monitoring to prevent accidental releases. Finished products earning the E1517 label undergo random sampling for both contaminants and adulteration, as consumer trust depends on clean, reliable sourcing. Downstream, logistics chains stretch from bulk tankers all the way to precision-tipped bottle fillers, each team owning its piece of the safety puzzle.

Application Area

If you look inside the toolkit of the modern food technologist, you’ll find diacetin filling roles in flavor enhancement, moisture retention, and the fine balance of texture. Chewing gum makers rely on it for softness and a slow, satisfying mouthfeel. Confectioners add it to fudge and toffee for pliability. Table spreads and low-fat mayonnaise gain a smoother feel thanks to its integration. Outside food, diacetin stands as a plasticizer in cellulose-based plastics and film coating agents, tuning materials for flexibility without imparting hazardous residues. Pharmaceutical suppliers tap it for solvent and excipient roles in capsules and tablets, noting both regulatory clarity and tolerable flavor. The cosmetic sector places it in skin lotions and hair conditioners, where it helps solubilize tricky active ingredients and keep them dispersed without greasiness. The presence of diacetin across so many products speaks to its adaptability as people demand healthier, safer, and longer-lasting consumer goods.

Research & Development

Research teams treat diacetin as more than a solved chapter. Laboratories focus energy on finding greener synthetic routes, using bio-derived acetic acid and glycerol streams from renewable sources. Pilot studies examine how modified acetins handle advanced tasks, such as boosting performance of bioplastics, emulsifying plant-based ingredients, or replacing fossil-derived solvents. Food scientists run experiments to fine-tune its impact in fat replacement or calorie-reduction projects, comparing sensory profiles with legacy formulations to make products both tastier and healthier. Academic chemical engineers explore how diacetin decomposes under composting and waste treatment conditions, testing its promise as an input for biodegradable polymer blends. Regulatory scientists review new toxicology and residue studies, updating both GRAS (Generally Recognized as Safe) conclusions and operational recommendations as datasets get richer. The steady pace of published research reveals not only scientific curiosity but industry’s determination to stay aligned with evolving sustainability and safety norms.

Toxicity Research

Safety evaluators take a conservative stance with diacetin. Acute and chronic toxicity studies, stretching back decades, show remarkably low risk at baseline levels found in foods or household goods. Rodent feeding experiments, repeat-dose studies, and metabolic tracking consistently report minimal health impacts and rapid breakdown in the digestive system. Regulatory authorities set Acceptable Daily Intake (ADI) levels at generous margins, validating diacetin for unrestricted use across global markets. Standard precautionary language on datasheets stays, reminding handlers to avoid inhalation or direct skin contact with undiluted forms, but these warnings seldom rise above those for edible oils or table acids. Ongoing studies take a sharper focus on vulnerable groups—infants, those with metabolic sensitivities, or workers in high-exposure industries—and safety reviews update periodically to keep up with advances in analytical methods and understanding of long-term exposure. Safety data supports continued inclusion in foods, health supplements, and personal care items, barring reckless overdosing or gross misuse.

Future Prospects

The next decade holds plenty of upside and challenge for diacetin. Consumer demand keeps shifting toward transparency, traceable supply chains, and bio-based alternatives. Sourcing teams dig into scalable routes using plant-sourced glycerol from non-GMO feedstocks and green acetic acid production, promising lower-carbon and non-toxic alternatives to standard petrochemical solvents and plasticizers. Product developers draw up recipes for next-generation snacks, low-sugar treats, and medical supplements that would falter without a reliable carrier, plasticizer, or flavor enhancer. Researchers pivot toward advanced applications in eco-friendly packaging, biocomposites, and medical encapsulation, where every advantage in biodegradability and low toxicity matters. Regulatory agencies stay busy—setting clearer ceilings on residual solvents, demanding traceable origins, requiring allergen-free certifications—as food safety and chemical transparency standards get tighter year by year. Early adopters enjoy a head start; those who lag may find supply chains and consumer trust running lean. Secret to long-term success lies in sharper science, honest safety testing, and commitment to making every bottle better for people and the planet.



What is Diacetin used for?

What Exactly Is Diacetin?

Diacetin, or glyceryl diacetate, doesn’t show up in casual conversation much, but it quietly plays a part in several industries. Chemists know it as a type of ester, made from glycerol and acetic acid. People might not recognize it on a label, though its uses reach into everyday products.

Everyday Applications People Overlook

Bakeries and food processors put Diacetin to use for practical reasons. This compound works well in food, acting as a plasticizer. In simple words, it helps keep food textures soft and pleasant. Diacetin often shows up in chewing gum, where it keeps flavors fresh and gums pliable. I remember reading ingredients at a corner store and being surprised that something so technical could help gum stay chewable longer. The food-grade status of Diacetin rests on safety reviews. Organizations, including the US Food and Drug Administration, have reviewed its safety and allow limited amounts in food.

The cosmetics world values materials that boost texture or lock in moisture, and Diacetin finds work here as well. Its humectant properties keep creams and lotions stable and smooth. A trip into a drugstore reveals how many personal care products try to stay shelf-stable and pleasant using all sorts of behind-the-scenes ingredients like this one.

Behind Industrial Curtains

Out in factories, Diacetin handles big jobs far from grocery shelves. Plastic manufacturers use it as a plasticizer to soften plastics. This trait matters for products that shouldn’t shatter or go brittle—think flexible PVC pipes, cables, or even some toys. On the pharmaceutical side, pill-makers use Diacetin to help tablets glide out of machines or to tweak how a pill dissolves in the stomach.

Every step involving Diacetin gets tested and monitored. I’ve seen strong documentation in industrial settings, where engineers keep records to stay within safety rules. Oversight helps prevent unwanted residues from drifting into finished products.

Sifting Out Misconceptions

A lot of ingredients with long technical names cause confusion. I’ve watched friends puzzle over ingredient lists, worried about which chemicals belong in food or skin products. A fact worth knowing: Diacetin breaks down into familiar substances, like acetic acid—a component found in vinegar—once inside the body. While some worry about “unknown chemicals,” substances such as Diacetin often pass safety checks before ever reaching a product.

Transparency helps everyone make smart choices. Detailed product labeling puts power in the hands of users. I usually recommend checking reputable sources or looking for reviews from scientific organizations when an unfamiliar substance pops up.

Paths Toward Safer, Smarter Use

Continued research should stay a priority. Scientists need updated data on how low levels of Diacetin behave long term, especially in food and care items. The regulatory system deserves respect, but it never hurts to keep asking questions. Consumer groups, chemists, and producers could work together to improve ingredient labeling or to fund studies looking at environmental impact.

Better conversations between industry and everyday folks bridge the trust gap. Sharing clear, evidence-based information about uses, standards, and safety gives everyone a fair chance to understand what goes into food and daily products. For my part, I find curiosity about ingredients pays off in confidence and peace of mind.

Is Diacetin safe for human consumption?

What is Diacetin?

Diacetin, also called glyceryl diacetate, shows up in some processed foods and even in cosmetics. Food makers use it for its texture-enhancing abilities, making foods smoother or creamier. When you spot lists with mono- and diacetin derivatives, you’re dealing with something that doesn’t occur naturally in many things we typically eat. That often sparks questions about what it does in the body.

How Regulators See Diacetin

The U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA) both pay close attention to additives like this. The FDA puts diacetin on its “Generally Recognized As Safe” (GRAS) list at low levels, usually below 500 mg/kg in food. EFSA set a daily intake limit of 50 mg/kg of body weight for diacetin along with its related esters.

That doesn't mean you can eat unlimited amounts. It means scientists have looked at doses people realistically eat and haven’t seen health problems so far. Lab studies in rats and mice have backed up these limits, showing no worrisome effects at expected levels. People who stick to “real” foods often avoid any risk, but for those who enjoy packaged snacks or ice cream, low-level exposure adds up over time.

Human Experience and Health Questions

Processed food has been part of my diet as long as I can remember. Packages get flipped over once I recognized how many unfamiliar ingredients wind up in daily snacks and sauces. Diacetin falls into that category—used because it’s cheap, stable, and efficient at holding ingredients together. Most people don’t notice it at all.

Concerns always ramp up when I see long chemical names in ingredient lists. Diacetin can break down into acetic acid (like vinegar) and glycerol in the body, both of which the human body handles all the time. Some people argue small amounts wouldn’t cause trouble, especially if your diet isn’t packed with processed foods. Still, research hasn’t produced long-term studies in humans, and that always leaves a gap for curiosity and worry.

Anyone with allergies to acetates or sensitive digestive systems might notice mild discomfort. For most adults, eating the occasional food with diacetin hasn’t produced clear links to illness. No strong evidence points to cancer, organ damage, or true toxicity in real-world servings. What people often overlook: each processed additive by itself may not harm you, but a diet loaded with additives over decades leaves unanswered questions.

Better Choices and Safer Consumption

Not every family can cut out processed snacks cold turkey. Time and budget pressures make these foods a regular part of many diets. The best way forward means reading labels, building meals mostly out of whole foods, and using packaged treats sparingly. Diacetin on its own in moderation doesn’t jump out as a major public health threat.

Researchers and food safety experts keep tabs on studies and reports, including new findings about what happens when additives pile up in the body. One thing that can help: ask your doctor or dietitian if certain preservatives clash with personal health needs or sensitivities. For now, I lean on common sense. Try to make the label shorter. If “diacetin” pops up every day, swap out a few convenience choices for something simple—like a piece of fruit or plain yogurt. Safe odds improve each time a fresh ingredient lands on your plate.

What is the chemical composition of Diacetin?

What Diacetin Really Is

Diacetin, or glyceryl diacetate, draws its structure from glycerol and acetic acid. It’s one of those chemicals that finds its way into quite a few industries but doesn’t often grab headlines. In the lab, it stands out as a clear, oily liquid. Chemically, diacetin carries the formula C7H12O5. That breaks down into seven carbon atoms, twelve hydrogens, and five oxygens. Look at the structure and you’ll see two acetyl (or acetate) groups bonded to a glycerol backbone. Nothing extra—just a clean, simple molecule that does its work quietly.

Why Knowing the Composition Matters

I’ve had plenty of conversations with people in food, cosmetics, and chemicals who admit they use diacetin without really considering the finer points of its makeup. These acetate groups aren’t just for show—they shift how the molecule interacts in different environments. In everyday products, these two acetyl groups help diacetin blend with other substances more easily and improve its function as a plasticizer, solvent, or stabilizer.

Chemical understanding doesn’t just help regulators. For product formulators and workers in production, knowing about those two acetate groups, and how they connect to the central glycerol, influences every step from mixing to shelf life. If one of those acetyl groups breaks off, you’re left with monoacetin and acetic acid as byproducts, both with different properties. This comes up when you consider stability under heat, light, or with other chemicals—something that matters for anybody storing or transporting finished goods.

Impacts in Food, Pharma, and Industry

Many people eat small quantities of diacetin without noticing, since it often appears as a food additive. The chemical backbone allows it to combine with fats in baked goods or candies, improving texture and extending shelf life. In the pharmaceutical world, its unique structure makes it handy for mixing in certain syrups and as a solvent for vitamins. Some adhesives and coatings rely on that same combination of glycerol and acetates to achieve the right balance of flexibility and durability.

I’ve found that not every manufacturer takes the time to confirm purity or breakdown products. In theory, diacetin breaks down in the body into harmless glycerol and acetic acid—two substances found in metabolism already. That said, this assumes the product doesn’t contain contaminants left from the manufacturing process. Currently, strict guidelines require testing for purity, and third-party labs exist to offer extra protection for consumers.

Paths Toward Better Transparency and Safety

The industry can improve by making information about diacetin’s origins, purity, and breakdown available. That means providing technical sheets with more than just the basics, keeping supply chains accountable, and investing in transparent analysis. Public health depends on both science and honest communication. As a consumer and someone who has worked with these products, I look for those who share lot-by-lot purity data and clear material safety sheets, not just basic specs.

Bridging the gap between producers, regulators, and end-users comes from clarity about what’s in the bottle and how that affects products down the line. Diacetin keeps proving that small molecules play a big part in our safety and daily routines—once you pay attention to what goes in, peace of mind follows.

What industries commonly use Diacetin?

Food and Beverage Manufacturing

Anyone who has worked behind the scenes in food processing knows that ingredients showing up in tiny percentages sometimes play a big role. Diacetin appears in some confectionary plants and flavor labs. Candy coatings need ingredients that handle both stickiness and texture—diacetin steps in to soften hard chews and manage mouthfeel without adding a strange taste. Some chewing gumsers and bakers lean on it for just enough flexibility so treats won’t chip your teeth. Food scientists count on diacetin’s characteristics—they call it a plasticizer—so they can get the right chew without risky chemicals.

Pharmaceuticals and Drug Formulation

Spend any time talking to pharmacists or researchers, and you’ll hear about binders and lubricants in pills. Formulating a tablet people can actually swallow is not just about what delivers the medicine. Diacetin gives tablet coatings a chance to bend rather than crack. Cold warehouses and vibrating packing lines can ruin batches if coatings split. Pharmacies depend on diacetin so capsules slide down smoothly and powder doesn’t clump inside machines. I’ve seen it included in trial batches for time-release capsules too, where a smooth, steady breakdown of medication is the end game.

Cosmetics and Personal Care

Most people don’t realize how much chemistry goes into a bottle of lotion or a stick of lipstick. Cosmetic chemists turn to diacetin to solve a few problems all at once. Lipsticks demand softness at room temperature but still need to set firm enough in your purse. Creams get a silkier texture and absorb better when diacetin helps mix up oil and water. Some personal care startups value the fact that diacetin keeps formulas flowing without relying on heavy petroleum derivatives. Product formulators highlight its record for safety: the scientific literature puts its irritation potential pretty low, compared to other synthetics.

Plastics and Industrial Uses

Factory workers and process engineers often deal with materials that must be both resilient and soft. Diacetin enters as a softener for plastics—PVC hoses and hoses in factory floors need flexibility in winter as well as summer. Wire and cable makers use it when flexibility is essential, so insulation can be applied smoothly around copper. Some companies run tests with diacetin in safety glass formulations, searching for a balance between strength and pliability. In adhesives, it can help glue hold on longer without turning brittle.

Printing Inks and Coatings

Print shops chase bright colors and smooth lines on boxes and labels. Formulators add diacetin so inks flow onto paper just right and don’t crack or peel during storage. Offset press operators tell stories of batches where one tiny tweak in ink consistency cuts down smudging and improves drying. Water-based coatings in packaging lines use diacetin to keep finishes from sticking together when cartons stack up on pallets.

The Safety Factor

Diacetin’s track record gets attention for being relatively low in toxicity. Regulatory agencies in the US and Europe set exposure limits that protect both workers and consumers. Food manufacturers and pharmaceutical companies follow strict quality controls, regularly testing for purity so nothing unexpected ends up in the supply chain. Cosmetic chemists keep tabs on new studies, but so far, diacetin hasn’t shown up on lists of major allergens or reproductive hazards.

Looking Forward

Industries choose diacetin for what it brings to the table: a reliable softening effect, mildness, and a long history in regulated products. Suppliers see demand shifting as trends move away from harsher chemicals. Environmental teams and product safety experts keep tabs on studies, ready to pivot if new evidence comes forward. For now, diacetin maintains its place in the toolkit for food, pharma, and manufacturers who need a nudge toward flexibility without compromising safety.

Are there any side effects associated with Diacetin?

Understanding What Diacetin Really Does

Diacetin, known scientifically as glyceryl diacetate, shows up in plenty of food products and sales catalogs. Food scientists appreciate its ability to keep certain foods from drying out and separating. You see it on ingredient lists for baked goods, candy, and even processed cheese. For years, manufacturers have counted on diacetin for moisture retention and texture. It also appears in industrial uses, though that's less relevant to most people's daily lives.

What Side Effects Come with Diacetin?

People naturally want to know what happens when they eat products with additives. That's common sense. In my experience working with food safety teams, few topics stir up as much concern as additives that fly under the public's radar.

For diacetin, the available studies tie its safety closely to how much we consume. The Joint FAO/WHO Expert Committee on Food Additives (JECFA) examined diacetin and found usual food exposure rates did not raise red flags for toxicity. Despite that, research on long-term effects in humans runs thin. Animal studies offer some evidence about what might happen with very large, unrealistic doses. Rats given enormous amounts showed some stomach irritation and minor changes in liver weight. Even so, those doses far exceed what anyone would get from a cheeseburger or loaf of bread.

Digestive discomfort stands out as the most common concern. Higher doses could lead to stomach aches, nausea, or diarrhea in sensitive people. Think of it a bit like eating too many sugar-free sweets; the body just isn't designed for huge amounts all at once. There’s no strong evidence of allergic reactions tied to diacetin, and the chemical does not linger or build up in the body over time. Unlike some artificial additives, diacetin breaks down fairly quickly.

Food Safety and Risk Assessment

Real peace of mind comes from knowing how food regulators approach new data. The FDA includes diacetin in its database of substances considered safe when used as directed. European food authorities landed at a similar judgment, but caution that manufacturers should keep concentrations low. Health Canada, as of the most recent review, has not reported public health incidents that link directly to diacetin in foods.

Staying Informed and Reducing Worry

Food choices today involve balancing convenience, flavor, shelf life, and health. Most questions about chemical additives grow out of people feeling cut off from what’s actually in their food. Rather than looking for total avoidance, I’ve found it helps to ask for transparency. Brands have a responsibility not just to follow safety limits, but to share information about how much additive goes into different foods and why. This lets folks make their own decisions with clear facts.

Researchers should keep looking into how the body handles diacetin, especially for people with digestive sensitivities or rare health conditions. At the same time, consumers who feel uneasy about synthetic additives might focus on foods with fewer processed ingredients and shorter ingredient lists. That’s something anyone can do, no matter their background.

Bringing Facts to the Table

Most people will never run into major trouble eating products with small amounts of diacetin. For those worried, awareness goes a long way. Reading labels, checking the latest guidance from trusted agencies, and asking manufacturers for details—these steps keep the focus on informed choices, not fear. Additives like diacetin exist in a world where facts and open communication matter most.

Diacetin
Names
Preferred IUPAC name 1,2,3-Trihydroxypropane 1,3-diacetate
Other names Glycerol diacetate
1,2-Diacetin
Diacetin
Diacetyl glycerol
Pronunciation /daɪˈæsɪtɪn/
Identifiers
CAS Number 25395-31-7
Beilstein Reference 1911070
ChEBI CHEBI:28656
ChEMBL CHEMBL135903
ChemSpider 15837904
DrugBank DB03627
ECHA InfoCard 03e6fe24-1e7e-4b29-8d47-799bda3e858f
EC Number 204-664-4
Gmelin Reference 202165
KEGG C19699
MeSH Glycerol.
PubChem CID 8533
RTECS number AF4200000
UNII 32G154D81X
UN number UN2627
Properties
Chemical formula C7H12O5
Molar mass 218.22 g/mol
Appearance Colourless transparent liquid
Odor Fruity
Density 1.170 g/cm3
Solubility in water miscible
log P -0.48
Vapor pressure 0.018 mmHg at 25 °C
Acidity (pKa) 13.52
Basicity (pKb) 6.87
Magnetic susceptibility (χ) -68.4×10⁻⁶ cm³/mol
Refractive index (nD) 1.431
Viscosity 20 mPa·s (20°C)
Dipole moment 2.9 D
Thermochemistry
Std molar entropy (S⦵298) 273.5 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) -1190.6 kJ/mol
Std enthalpy of combustion (ΔcH⦵298) -3022.4 kJ/mol
Pharmacology
ATC code A21AA11
Hazards
Main hazards Harmful if swallowed. Causes serious eye irritation. May cause respiratory irritation.
GHS labelling GHS02, GHS07
Pictograms GHS07
Signal word Warning
Hazard statements H319: Causes serious eye irritation.
Precautionary statements P264, P280, P305+P351+P338, P337+P313
NFPA 704 (fire diamond) 1-1-0
Flash point 145 °C
Autoignition temperature 570 °C
Lethal dose or concentration LD50 (oral, rat): 15,400 mg/kg
LD50 (median dose) 2050 mg/kg (rat, oral)
NIOSH RX3675000
PEL (Permissible) PEL (Permissible exposure limit) for Diacetin: Not established
REL (Recommended) 600 mg/kg bw
Related compounds
Related compounds Triacetin
Monoacetin
Glycerol
Acetic acid