Material Safety Data Sheet: Calcium Acetate Monohydrate

Identification

Product Name: Calcium Acetate Monohydrate
Synonyms: Acetic acid calcium salt monohydrate, calcium diacetate monohydrate
Chemical Formula: C4H6CaO4•H2O
CAS Number: 5743-26-0
Supplier: Manufacturer or distributor details with address and emergency phone number
Recommended Uses: Used in food additives, pharmaceuticals, laboratory chemical, and as a buffer or stabilizer

Hazard Identification

GHS Classification: Not classified as hazardous according to OSHA Hazard Communication Standard (29 CFR 1910.1200)
Hazard Statements: No significant immediate hazards identified under normal conditions; can cause mild irritation to eyes, skin or respiratory system upon high exposure
Precautionary Statements: Avoid inhalation, use in well-ventilated areas, wash thoroughly after handling
Signal Word: None required for this substance
Physical Hazards: Non-flammable, stable powder or granular solid
Health Hazards: Dust may cause mechanical irritation to eyes, nose, and respiratory tract
Environmental Hazards: Not expected to pose risks to the environment in normal laboratory or industrial quantities

Composition / Information on Ingredients

Chemical Name: Calcium Acetate Monohydrate
Concentration: 99–100% Pure
Impurities: Trace levels of naturally occurring elements may be present in negligible amounts
CAS Number: 5743-26-0
Molecular Weight: 176.19 g/mol

First Aid Measures

Inhalation: Move affected person to fresh air, keep at rest. Seek medical attention if irritation persists
Skin Contact: Wash skin gently and thoroughly with soap and water. Remove contaminated clothing
Eye Contact: Immediately flush with plenty of water for at least 15 minutes. Remove contact lenses if present and easy to do. Get medical help if irritation continues
Ingestion: Rinse mouth with water. Do not induce vomiting unless instructed by a healthcare provider. Seek medical attention for persistent symptoms
Most Important Symptoms: Mild irritation of eyes, skin, or respiratory system; no systemic toxicity generally expected from routine exposure

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide
Unsuitable Media: No specific restrictions; avoid strong water jet that might spread the substance
Special Hazards from Fire: Calcium acetate itself is not flammable; under fire conditions oxides of carbon may form; can flow with water runoff
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear to prevent contact with skin and eyes
Additional Information: Avoid breathing combustion fumes, prevent run-off from entering drains or waterways

Accidental Release Measures

Personal Precautions: Avoid dust formation, ensure adequate ventilation; wear appropriate protective equipment such as gloves, goggles, and a dust mask
Environmental Precautions: Prevent further leakage if safe to do so. Do not allow material to enter drains, surface or ground water
Methods for Clean-Up: Sweep up and shovel into suitable containers for disposal; avoid creating airborne dust. Wash spill area with water to remove residues
Other Information: Use non-sparking tools and equipment to reduce the chance of contamination with incompatible materials

Handling and Storage

Handling: Use in areas with good ventilation, avoid breathing dust, and minimize contact with skin and eyes. Handle with care to prevent spills and dust emissions
Storage Conditions: Store tightly closed in a cool, dry, well-ventilated place. Keep apart from acids and oxidizing agents
Incompatible Materials: Strong acids, strong oxidizing agents
Specific Storage Guidelines: Store in original packaging or compatible containers made from polyethylene, glass, or stainless steel. Clearly label containers
Hygiene Requirements: Wash hands thoroughly after handling, keep work area clean, eat or drink only away from workspaces

Exposure Controls and Personal Protection

Occupational Exposure Limits: No OSHA PEL or ACGIH TLV established; use dust limits as for particulate not otherwise classified (PNOC): 15 mg/m³ (total dust), 5 mg/m³ (respirable fraction)
Engineering Controls: Local exhaust ventilation, process enclosure or other engineering controls to control airborne levels below recommended limits
Personal Protective Equipment: Respiratory protection:
NIOSH-approved dust mask or respirator if dust generation likely
Hand protection:
Chemical-resistant gloves
Eye protection:
Safety goggles or face shield
Skin and body protection:
Protective clothing (lab coat or apron) to minimize skin contact
Hygienic Measures: Wash hands, forearms, and face thoroughly after handling; avoid eating, drinking, or smoking in work area

Physical and Chemical Properties

Appearance: White, odorless, crystalline powder or granular solid
Odor: Odorless
pH (5% solution): Between 7.0–9.0
Melting Point: Approximately 160°C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Solubility in Water: Soluble, approximately 39 g/100 mL at 0°C
Density: About 1.5 g/cm³
Flash Point: Not flammable
Vapor Pressure: Not applicable
Partition Coefficient: Not available
Evaporation Rate: Not applicable
Auto-ignition Temperature: Not applicable

Stability and Reactivity

Chemical Stability: Stable under normal temperatures and recommended storage conditions
Reactivity: Reacts with strong acids to release acetic acid; contact with strong oxidizers may generate heat or cause reactions
Hazardous Reactions: No polymerization expected. Mixing with water produces a mildly alkaline solution
Conditions to Avoid: Excessive heat, direct sunlight, humidity, contact with incompatible materials
Incompatible Materials: Strong acids, oxidizing agents
Decomposition Products: Carbon dioxide, carbon monoxide, calcium oxide may form if heated to decomposition

Toxicological Information

Acute Toxicity: Low toxicity, estimated oral LD50 (rat) >2000 mg/kg; large doses may cause mild gastrointestinal discomfort
Skin Contact: No significant irritation expected in normal use; prolonged contact may cause minor irritation
Eye Contact: Dust may cause mechanical irritation, redness, or discomfort
Inhalation: High dust concentrations may irritate the respiratory tract
Chronic Effects: No evidence of sensitization or chronic health effects in humans under ordinary exposure
Carcinogenicity: Not listed by IARC, NTP, or OSHA as a carcinogen
Additional Data: Calcium acetate is metabolized to calcium and acetic acid, both substances found naturally in the body

Ecological Information

Ecotoxicity: Not toxic to aquatic organisms at typical concentrations
Persistence and Degradability: Readily dissociates and is biodegradable; not expected to accumulate in the environment
Bioaccumulation: Does not bioaccumulate; calcium and acetate ions are part of normal biogeochemical cycles
Mobility in Soil: Highly soluble; can migrate easily in water and soil, but environmental hazard is limited due to low toxicity and natural occurrence of ions
Other Adverse Effects: No known significant effects on the ozone layer or climate change

Disposal Considerations

Waste Treatment Methods: Collect and place in suitable containers for disposal following local, state, and federal regulations
Disposal of Product: Material may be dissolved in large quantities of water and discharged to sewer if permitted by regulations. For large amounts, use licensed chemical waste disposal contractor
Disposal of Contaminated Packaging: Rinse thoroughly, then recycle or dispose as non-hazardous waste depending on guidelines
Special Precautions for Disposal: Avoid release into the environment; follow applicable regulations regarding disposal of chemicals

Transport Information

UN Number: Not regulated as a hazardous material for transportation
Transport Hazard Class: Not classified as dangerous goods by ADR/RID/IMDG/IATA
Packing Group: Not applicable
Proper Shipping Name: Calcium Acetate Monohydrate
Environmental Hazards: None
Special Transport Precautions: Protect from humidity, secure packaging to avoid rupture and spillage during transit

Regulatory Information

US Federal Regulations: Not subject to SARA Title III Section 302/304/313 reporting, not listed as a hazardous substance under CERCLA
TSCA Status: Listed on the Toxic Substances Control Act (TSCA) inventory
California Proposition 65: Not listed
OSHA Regulatory Status: Not hazardous according to OSHA criteria
EU Regulations: Not classified as dangerous according to Regulation (EC) No 1272/2008 (CLP); listed on EINECS (EC No. 209-013-2)
Canadian Regulations: Listed on Canadian DSL, not subject to WHMIS classification
Other International Inventories: Present on AICS (Australia), NZIoC (New Zealand), ENCS (Japan), PICCS (Philippines), KECL (Korea)